#14 - Aug. 20, 2010, 6:53 a.m.
I'd recommend both a good anti-spam filter, and really - a new, totally unrelated email address should help this.
If you've ever replied to even one phish, I'd personally just close that account and walk away, they know it's 'live' and this won't ever stop.
Making sure you have no spyware on your system is also critical. Some otherwise innocuous programs look for emails and ship them off. Not directly harmful, but that's where a lot of this comes from. Doesn't even have to be on your system if anyone else has your email in their contact list it could have been scanned from there.
In a spam filter, look for one that looks at the actual sender - not just the FROM line in an email as that can be very easily spoofed with a legitimate address.