#9 - Jan. 23, 2010, 6:09 p.m.
There's a bad setting somewhere (either your mouse software or the game is running elevated, but it's usually the game) and it's preventing the two from talking to one another. You can try turning on UAC, then right-click your World of Warcraft shortcut and go to Properties. Go to the Compatibility tab and make sure the run as administrator option isn't checked. Restarting the computer and then double-clicking on the shortcut should make it work.